Snakes on a Plane, but this go-around we've got terrorists who unwittingly choose to hijack the one plane in the air with a bloodsucking mama bear who's gotten pretty darn good over the years at managing her pangs as if she simply had diabetes or something.
Adding insult to injury, everyone she bites goes vampiric within a minute or two, so pretty soon we've got full-fledged Vampires on a Plane feeling pretty snacky.
Needless to say, it's a bloodbath that gives a whole new meaning to catching the red-eye!